Website Image (IUPUI Department of Biology, Human Chromosomal Disorders, April 30, 2003):
[karyotype of a human cell with an extra chromosome on chromosome #18]. Retrieved April 16, 2015
from http://www.biology.iupui.edu/biocourses/N100/2k2humancsomaldisorders.html
[karyotype of a human cell with an extra chromosome on chromosome #18]. Retrieved April 16, 2015
from http://www.biology.iupui.edu/biocourses/N100/2k2humancsomaldisorders.html
Statistics:
This disorder occurs occurred in fetuses, making it very difficult for them to survive until their. The age onset of Trisomy 18 is:
Race/ethnicity has not been reported to influence the risk of Edwards Syndrome.
A study was conducted of the four ethnic groups (white, Far East Asian, Pacific Islander, Filipino), and the highest risk for Trisomy 18 was from the Far East Asians, and lowest risk for the Pacific Islanders. It was later realized that the differences in risk appeared due to differences in maternal age.
Outcomes of Disorder:
Trisomy 18 is very life-threatening and dangerous. Newborns have a 40% chance of surviving to age 1 month, infants only have a 5% chance of surviving to age 1 year and children have a 1% chance of surviving to age 10 years.
- Occurs in about 1 in 2500 pregnancies in the US
- Occurs in about 1 in 5,000 live-born infants
- Only about 50% of babies who are carried to term will be born alive
- Only 5 to 10% of children with this condition live past their first year, suffering challenging disabilities
- Around 80% affected are female
- Risk of having a baby with Trisomy 18 increases with mother's age. Average age of mother at pregnancy with a kid that has Trisomy 18 is between 18 to 32 years old.
This disorder occurs occurred in fetuses, making it very difficult for them to survive until their. The age onset of Trisomy 18 is:
- Antenantal - During pregnancy
- Neonatal - Newborns
Race/ethnicity has not been reported to influence the risk of Edwards Syndrome.
A study was conducted of the four ethnic groups (white, Far East Asian, Pacific Islander, Filipino), and the highest risk for Trisomy 18 was from the Far East Asians, and lowest risk for the Pacific Islanders. It was later realized that the differences in risk appeared due to differences in maternal age.
Outcomes of Disorder:
Trisomy 18 is very life-threatening and dangerous. Newborns have a 40% chance of surviving to age 1 month, infants only have a 5% chance of surviving to age 1 year and children have a 1% chance of surviving to age 10 years.